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The NK1 Receptor Antagonist L822429 Reduces Heroin Reinforcement

Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is unknown whether pharmacological NK1R blockade has the same effect. Here, we examined the effect of L822429, a rat-specific NK1R antagonist, on the reinforcing properties o...

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Dettagli Bibliografici
Autori principali: Barbier, Estelle, Vendruscolo, Leandro F, Schlosburg, Joel E, Edwards, Scott, Juergens, Nathan, Park, Paula E, Misra, Kaushik K, Cheng, Kejun, Rice, Kenner C, Schank, Jesse, Schulteis, Gery, Koob, George F, Heilig, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629386/
https://ncbi.nlm.nih.gov/pubmed/23303056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.261
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