The NK1 Receptor Antagonist L822429 Reduces Heroin Reinforcement

Genetic deletion of the neurokinin 1 receptor (NK1R) has been shown to decrease the reinforcing properties of opioids, but it is unknown whether pharmacological NK1R blockade has the same effect. Here, we examined the effect of L822429, a rat-specific NK1R antagonist, on the reinforcing properties o...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Barbier, Estelle, Vendruscolo, Leandro F, Schlosburg, Joel E, Edwards, Scott, Juergens, Nathan, Park, Paula E, Misra, Kaushik K, Cheng, Kejun, Rice, Kenner C, Schank, Jesse, Schulteis, Gery, Koob, George F, Heilig, Markus
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629386/
https://ncbi.nlm.nih.gov/pubmed/23303056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2012.261
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires