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Development of Mechanical Hypersensitivity in Rats During Heroin and Ethanol Dependence: Alleviation by CRF(1) Receptor Antagonism
Animal models of drug dependence have described both reductions in brain reward processes and potentiation of stress-like (or anti-reward) mechanisms, including a recruitment of corticotropin-releasing factor (CRF) signaling. Accordingly, chronic exposure to opiates often leads to the development of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262951/ https://ncbi.nlm.nih.gov/pubmed/22119954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.11.006 |
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