Development of Mechanical Hypersensitivity in Rats During Heroin and Ethanol Dependence: Alleviation by CRF(1) Receptor Antagonism

Animal models of drug dependence have described both reductions in brain reward processes and potentiation of stress-like (or anti-reward) mechanisms, including a recruitment of corticotropin-releasing factor (CRF) signaling. Accordingly, chronic exposure to opiates often leads to the development of...

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Bibliographische Detailangaben
Hauptverfasser: Edwards, Scott, Vendruscolo, Leandro F., Schlosburg, Joel E., Misra, Kaushik K., Wee, Sunmee, Park, Paula E., Schulteis, Gery, Koob, George F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262951/
https://ncbi.nlm.nih.gov/pubmed/22119954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.11.006
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