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Chronic CRF(1) Receptor Blockade Reduces Heroin Intake Escalation and Dependence-Induced Hyperalgesia
Opioids represent effective drugs for the relief of pain, yet chronic opioid use often leads to a state of increased sensitivity to pain that is exacerbated during withdrawal. A sensitization of pain-related negative affect has been hypothesized to closely interact with addiction mechanisms. Neuroad...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057367/ https://ncbi.nlm.nih.gov/pubmed/24330252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12120 |
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