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Chimeric GII.4 Norovirus Virus-Like-Particle-Based Vaccines Induce Broadly Blocking Immune Responses

There is currently no licensed vaccine for noroviruses, and development is hindered, in part, by an incomplete understanding of the host adaptive immune response to these highly heterogeneous viruses and rapid GII.4 norovirus molecular evolution. Emergence of a new predominant GII.4 norovirus strain...

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Autores principales: Debbink, Kari, Lindesmith, Lisa C., Donaldson, Eric F., Swanstrom, Jesica, Baric, Ralph S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054422/
https://ncbi.nlm.nih.gov/pubmed/24741081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00785-14
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