Emergence of a Norovirus GII.4 Strain Correlates with Changes in Evolving Blockade Epitopes

The major capsid protein of norovirus GII.4 strains is evolving rapidly, resulting in epidemic strains with altered antigenicity. GII.4.2006 Minerva strains circulated at pandemic levels in 2006 and persisted at lower levels until 2009. In 2009, a new GII.4 variant, GII.4.2009 New Orleans, emerged a...

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Detalhes bibliográficos
Main Authors: Lindesmith, Lisa C., Costantini, Verónica, Swanstrom, Jesica, Debbink, Kari, Donaldson, Eric F., Vinjé, Jan, Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571402/
https://ncbi.nlm.nih.gov/pubmed/23269783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03106-12
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