Particle Conformation Regulates Antibody Access to a Conserved GII.4 Norovirus Blockade Epitope

GII.4 noroviruses (NoVs) are the primary cause of epidemic viral acute gastroenteritis. One primary obstacle to successful NoV vaccination is the extensive degree of antigenic diversity among strains. The major capsid protein of GII.4 strains is evolving rapidly, resulting in the emergence of new st...

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Detalhes bibliográficos
Main Authors: Lindesmith, Lisa C., Donaldson, Eric F., Beltramello, Martina, Pintus, Stefania, Corti, Davide, Swanstrom, Jesica, Debbink, Kari, Jones, Taylor A., Lanzavecchia, Antonio, Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136251/
https://ncbi.nlm.nih.gov/pubmed/24872579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01192-14
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