Particle Conformation Regulates Antibody Access to a Conserved GII.4 Norovirus Blockade Epitope

GII.4 noroviruses (NoVs) are the primary cause of epidemic viral acute gastroenteritis. One primary obstacle to successful NoV vaccination is the extensive degree of antigenic diversity among strains. The major capsid protein of GII.4 strains is evolving rapidly, resulting in the emergence of new st...

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Bibliografische gegevens
Hoofdauteurs: Lindesmith, Lisa C., Donaldson, Eric F., Beltramello, Martina, Pintus, Stefania, Corti, Davide, Swanstrom, Jesica, Debbink, Kari, Jones, Taylor A., Lanzavecchia, Antonio, Baric, Ralph S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136251/
https://ncbi.nlm.nih.gov/pubmed/24872579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01192-14
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