Particle Conformation Regulates Antibody Access to a Conserved GII.4 Norovirus Blockade Epitope

GII.4 noroviruses (NoVs) are the primary cause of epidemic viral acute gastroenteritis. One primary obstacle to successful NoV vaccination is the extensive degree of antigenic diversity among strains. The major capsid protein of GII.4 strains is evolving rapidly, resulting in the emergence of new st...

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Détails bibliographiques
Auteurs principaux: Lindesmith, Lisa C., Donaldson, Eric F., Beltramello, Martina, Pintus, Stefania, Corti, Davide, Swanstrom, Jesica, Debbink, Kari, Jones, Taylor A., Lanzavecchia, Antonio, Baric, Ralph S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136251/
https://ncbi.nlm.nih.gov/pubmed/24872579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01192-14
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