Within-Host Evolution Results in Antigenically Distinct GII.4 Noroviruses

Genogroup II, genotype 4 (GII.4) noroviruses are known to rapidly evolve, with the emergence of a new primary strain every 2 to 4 years as herd immunity to the previously circulating strain is overcome. Because viral genetic diversity is higher in chronic than in acute infection, chronically infecte...

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Autores principales: Debbink, Kari, Lindesmith, Lisa C., Ferris, Martin T., Swanstrom, Jesica, Beltramello, Martina, Corti, Davide, Lanzavecchia, Antonio, Baric, Ralph S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054459/
https://ncbi.nlm.nih.gov/pubmed/24648459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00203-14
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