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Chimeric GII.4 Norovirus Virus-Like-Particle-Based Vaccines Induce Broadly Blocking Immune Responses

There is currently no licensed vaccine for noroviruses, and development is hindered, in part, by an incomplete understanding of the host adaptive immune response to these highly heterogeneous viruses and rapid GII.4 norovirus molecular evolution. Emergence of a new predominant GII.4 norovirus strain...

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Autors principals: Debbink, Kari, Lindesmith, Lisa C., Donaldson, Eric F., Swanstrom, Jesica, Baric, Ralph S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054422/
https://ncbi.nlm.nih.gov/pubmed/24741081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00785-14
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