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Chimeric GII.4 Norovirus Virus-Like-Particle-Based Vaccines Induce Broadly Blocking Immune Responses

There is currently no licensed vaccine for noroviruses, and development is hindered, in part, by an incomplete understanding of the host adaptive immune response to these highly heterogeneous viruses and rapid GII.4 norovirus molecular evolution. Emergence of a new predominant GII.4 norovirus strain...

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Autori principali: Debbink, Kari, Lindesmith, Lisa C., Donaldson, Eric F., Swanstrom, Jesica, Baric, Ralph S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054422/
https://ncbi.nlm.nih.gov/pubmed/24741081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00785-14
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