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Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
BACKGROUND: 5-methylcytosine (mC) can be oxidized by the tet methylcytosine dioxygenase (Tet) family of enzymes to 5-hydroxymethylcytosine (hmC), which is an intermediate of mC demethylation and may also be a stable epigenetic modification that influences chromatin structure. hmC is particularly abu...
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053808/ https://ncbi.nlm.nih.gov/pubmed/24594098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-3-r49 |
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