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Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming
Previous studies have revealed that mouse primordial germ cells (PGCs) undergo genome-wide DNA methylation reprogramming to reset the epigenome for totipotency. However, the precise 5-methylcytosine (5mC) dynamics and its relationship with the generation of 5-hydroxymethylcytosine (5hmC) are not cle...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3587712/ https://ncbi.nlm.nih.gov/pubmed/23399596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.22 |
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