Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during pronuclear development in equine zygotes produced by ICSI

BACKGROUND: Global epigenetic reprogramming is considered to be essential during embryo development to establish totipotency. In the classic model first described in the mouse, the genome-wide DNA demethylation is asymmetric between the paternal and the maternal genome. The paternal genome undergoes...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Epigenetics Chromatin
Autori principali: Heras, Sonia, Smits, Katrien, De Schauwer, Catharina, Van Soom, Ann
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353960/
https://ncbi.nlm.nih.gov/pubmed/28331549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0120-x
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