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5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.

BACKGROUND: In the mouse zygote, DNA methylation patterns are heavily modified, and differ between the maternal and paternal pronucleus. Demethylation of the paternal genome has been described as an active and replication-independent process, although the mechanisms responsible for it remain elusive...

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Autors principals: Juliette Salvaing, Tiphaine Aguirre-Lavin, Claire Boulesteix, Gaëtan Lehmann, Pascale Debey, Nathalie Beaujean
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC3364968?pdf=render
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