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5′-methylcytosine and 5′-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote

Covalent modification of cytosine nucleotides within the genome encode essential epigenetic information, with methylation (5meC) and hydroxymethylation (5hmC) having received most attention. It has been proposed that the formation of 5hmC is an intermediate in the active demethylation of 5meC. Some...

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Detalhes bibliográficos
Main Authors: Li, Yan, O’Neill, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653832/
https://ncbi.nlm.nih.gov/pubmed/23691085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063689
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