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5′-methylcytosine and 5′-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote

Covalent modification of cytosine nucleotides within the genome encode essential epigenetic information, with methylation (5meC) and hydroxymethylation (5hmC) having received most attention. It has been proposed that the formation of 5hmC is an intermediate in the active demethylation of 5meC. Some...

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Main Authors: Li, Yan, O’Neill, Chris
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653832/
https://ncbi.nlm.nih.gov/pubmed/23691085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063689
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