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Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition
DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides through repeat-variable diresidues. These repeat-variable diresidues form direct and sequence-specific contacts to DNA bases; hence, TALE–DNA interaction is sensitive to DN...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638953/ https://ncbi.nlm.nih.gov/pubmed/29026078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00860-6 |
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