Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain

BACKGROUND: 5-methylcytosine (mC) can be oxidized by the tet methylcytosine dioxygenase (Tet) family of enzymes to 5-hydroxymethylcytosine (hmC), which is an intermediate of mC demethylation and may also be a stable epigenetic modification that influences chromatin structure. hmC is particularly abu...

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Detalhes bibliográficos
Main Authors: Wen, Lu, Li, Xianlong, Yan, Liying, Tan, Yuexi, Li, Rong, Zhao, Yangyu, Wang, Yan, Xie, Jingcheng, Zhang, Yan, Song, Chunxiao, Yu, Miao, Liu, Xiaomeng, Zhu, Ping, Li, Xiaoyu, Hou, Yu, Guo, Hongshan, Wu, Xinglong, He, Chuan, Li, Ruiqiang, Tang, Fuchou, Qiao, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053808/
https://ncbi.nlm.nih.gov/pubmed/24594098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-3-r49
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