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Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes
INTRODUCTION: Signal transducer and activator of transcripton-5a (Stat5a) and its close homologue, Stat5b, mediate key physiological effects of prolactin and growth hormone in mammary glands. In breast cancer, loss of nuclear localized and tyrosine phosphorylated Stat5a/b is associated with poor pro...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
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BioMed Central
2012
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053108/ https://ncbi.nlm.nih.gov/pubmed/23036105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3328 |
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