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Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes

INTRODUCTION: Signal transducer and activator of transcripton-5a (Stat5a) and its close homologue, Stat5b, mediate key physiological effects of prolactin and growth hormone in mammary glands. In breast cancer, loss of nuclear localized and tyrosine phosphorylated Stat5a/b is associated with poor pro...

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書誌詳細
主要な著者: Peck, Amy R, Witkiewicz, Agnieszka K, Liu, Chengbao, Klimowicz, Alexander C, Stringer, Ginger A, Pequignot, Edward, Freydin, Boris, Yang, Ning, Ertel, Adam, Tran, Thai H, Girondo, Melanie A, Rosenberg, Anne L, Hooke, Jeffrey A, Kovatich, Albert J, Shriver, Craig D, Rimm, David L, Magliocco, Anthony M, Hyslop, Terry, Rui, Hallgeir
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053108/
https://ncbi.nlm.nih.gov/pubmed/23036105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3328
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