Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment

INTRODUCTION: Emerging evidence in estrogen receptor-positive breast cancer supports the notion that prolactin-Stat5 signaling promotes survival and maintenance of differentiated luminal cells, and loss of nuclear tyrosine phosphorylated Stat5 (Nuc-pYStat5) in clinical breast cancer is associated wi...

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Detalhes bibliográficos
Main Authors: Yang, Ning, Liu, Chengbao, Peck, Amy R, Girondo, Melanie A, Yanac, Alicia F, Tran, Thai H, Utama, Fransiscus E, Tanaka, Takemi, Freydin, Boris, Chervoneva, Inna, Hyslop, Terry, Kovatich, Albert J, Hooke, Jeffrey A, Shriver, Craig D, Rui, Hallgeir
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978581/
https://ncbi.nlm.nih.gov/pubmed/24004716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3467
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