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PTP1B Suppresses Prolactin Activation of Stat5 in Breast Cancer Cells
Basal levels of nuclear localized, tyrosine phosphorylated Stat5 are present in healthy human breast epithelia. In contrast, Stat5 phosphorylation is frequently lost during breast cancer progression, a finding that correlates with loss of histological differentiation and poor patient prognosis. Iden...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993292/ https://ncbi.nlm.nih.gov/pubmed/20952588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090399 |
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