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Pore Dynamics and Conductance of RyR1 Transmembrane Domain

Ryanodine receptors (RyR) are calcium release channels, playing a major role in the regulation of muscular contraction. Mutations in skeletal muscle RyR (RyR1) are associated with congenital diseases such as malignant hyperthermia and central core disease (CCD). The absence of high-resolution struct...

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Dettagli Bibliografici
Autori principali: Shirvanyants, David, Ramachandran, Srinivas, Mei, Yingwu, Xu, Le, Meissner, Gerhard, Dokholyan, Nikolay V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052289/
https://ncbi.nlm.nih.gov/pubmed/24896116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.023
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