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Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

Ryanodine receptor type 1 (RyR1) produces spatially and temporally defined Ca(2+) signals in several cell types. How signals received in the cytoplasmic domain are transmitted to the ion gate and how the channel gates are unknown. We used EGTA or neuroactive PCB 95 to stabilize the full closed or op...

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Bibliografiska uppgifter
Huvudupphovsmän: Samsó, Montserrat, Feng, Wei, Pessah, Isaac N, Allen, P. D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672603/
https://ncbi.nlm.nih.gov/pubmed/19402748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000085
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