RyR1/RyR3 Chimeras Reveal that Multiple Domains of RyR1 Are Involved in Skeletal-Type E-C Coupling

Skeletal-type E-C coupling is thought to require a direct interaction between RyR1 and the α(1S)-DHPR. Most available evidence suggests that the cytoplasmic II–III loop of the dihydropyridine receptor (DHPR) is the primary source of the orthograde signal. However, identification of the region(s) of...

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Библиографические подробности
Главные авторы: Perez, Claudio F., Voss, Andrew, Pessah, Isaac N., Allen, Paul D.
Формат: Artigo
Язык:Inglês
Опубликовано: Biophysical Society 2003
Предметы:
Cell Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302832/
https://ncbi.nlm.nih.gov/pubmed/12668474
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