Pore Dynamics and Conductance of RyR1 Transmembrane Domain

Ryanodine receptors (RyR) are calcium release channels, playing a major role in the regulation of muscular contraction. Mutations in skeletal muscle RyR (RyR1) are associated with congenital diseases such as malignant hyperthermia and central core disease (CCD). The absence of high-resolution struct...

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Detalhes bibliográficos
Main Authors: Shirvanyants, David, Ramachandran, Srinivas, Mei, Yingwu, Xu, Le, Meissner, Gerhard, Dokholyan, Nikolay V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052289/
https://ncbi.nlm.nih.gov/pubmed/24896116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.023
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