Pore Dynamics and Conductance of RyR1 Transmembrane Domain

Ryanodine receptors (RyR) are calcium release channels, playing a major role in the regulation of muscular contraction. Mutations in skeletal muscle RyR (RyR1) are associated with congenital diseases such as malignant hyperthermia and central core disease (CCD). The absence of high-resolution struct...

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Bibliografiska uppgifter
Huvudupphovsmän: Shirvanyants, David, Ramachandran, Srinivas, Mei, Yingwu, Xu, Le, Meissner, Gerhard, Dokholyan, Nikolay V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2014
Ämnen:
Channels and Transporters
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052289/
https://ncbi.nlm.nih.gov/pubmed/24896116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.023
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