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Pore Dynamics and Conductance of RyR1 Transmembrane Domain
Ryanodine receptors (RyR) are calcium release channels, playing a major role in the regulation of muscular contraction. Mutations in skeletal muscle RyR (RyR1) are associated with congenital diseases such as malignant hyperthermia and central core disease (CCD). The absence of high-resolution struct...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052289/ https://ncbi.nlm.nih.gov/pubmed/24896116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.023 |
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