Junctional trafficking and restoration of retrograde signaling by the cytoplasmic RyR1 domain

The type 1 ryanodine receptor (RyR1) in skeletal muscle is a homotetrameric protein that releases Ca(2+) from the sarcoplasmic reticulum (SR) in response to an “orthograde” signal from the dihydropyridine receptor (DHPR) in the plasma membrane (PM). Additionally, a “retrograde” signal from RyR1 incr...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Polster, Alexander, Perni, Stefano, Filipova, Dilyana, Moua, Ong, Ohrtman, Joshua D., Bichraoui, Hicham, Beam, Kurt G., Papadopoulos, Symeon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806685/
https://ncbi.nlm.nih.gov/pubmed/29284662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201711879
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