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Sequence Differences in the IQ Motifs of Ca(V)1.1 and Ca(V)1.2 Strongly Impact Calmodulin Binding and Calcium-dependent Inactivation
The proximal C terminus of the cardiac L-type calcium channel (Ca(V)1.2) contains structural elements important for the binding of calmodulin (CaM) and calcium-dependent inactivation, and exhibits extensive sequence conservation with the corresponding region of the skeletal L-type channel (Ca(V)1.1)...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570861/ https://ncbi.nlm.nih.gov/pubmed/18718913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805152200 |
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