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Sequence Differences in the IQ Motifs of Ca(V)1.1 and Ca(V)1.2 Strongly Impact Calmodulin Binding and Calcium-dependent Inactivation

The proximal C terminus of the cardiac L-type calcium channel (Ca(V)1.2) contains structural elements important for the binding of calmodulin (CaM) and calcium-dependent inactivation, and exhibits extensive sequence conservation with the corresponding region of the skeletal L-type channel (Ca(V)1.1)...

詳細記述

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書誌詳細
主要な著者: Ohrtman, Joshua, Ritter, Barbara, Polster, Alexander, Beam, Kurt G., Papadopoulos, Symeon
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570861/
https://ncbi.nlm.nih.gov/pubmed/18718913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805152200
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