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Hydrogels with Differential and Patterned Mechanics to Study Stiffness-Mediated Myofibroblastic Differentiation of Hepatic Stellate Cells

The differentiation of hepatic stellate cells (HSCs) into myofbroblasts is a key event in liver fibrosis. Due to the local stiffening of the extracellular matrix (ECM) during fibrosis, it is of great interest to develop mimics that can be used to investigate the cellular response to changes in mecha...

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Библиографические подробности
Главные авторы: Guvendiren, Murat, Perepelyuk, Maryna, Wells, Rebecca G., Burdick, Jason A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045659/
https://ncbi.nlm.nih.gov/pubmed/24361340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2013.11.008
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