Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins

Por Perepelyuk, Maryna, Maher, Christina, Lakshmikuttyamma, Ashakumary, Shoyele, Sunday A
Publicado no Int J Nanomedicine (2016)

Hydrogels with Differential and Patterned Mechanics to Study Stiffness-Mediated Myofibroblastic Differentiation of Hepatic Stellate Cells

Por Guvendiren, Murat, Perepelyuk, Maryna, Wells, Rebecca G., Burdick, Jason A.
Publicado em 2013

Isolation of Rat Portal Fibroblasts by In situ Liver Perfusion

Por Wen, Jessica W., Olsen, Abby L., Perepelyuk, Maryna, Wells, Rebecca G.
Publicado em 2012

Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation

Por Dim, Nneka, Perepelyuk, Maryna, Gomes, Olukayode, Thangavel, Chellappagounder, Liu, Yi, Den, Robert, Lakshmikuttyamma, Ashakumary, Shoyele, Sunday A.
Publicado no J Nanobiotechnology (2015)

Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression

Por Caliari, Steven R., Perepelyuk, Maryna, Soulas, Elizabeth M., Lee, Gi Yun, Wells, Rebecca G., Burdick, Jason A.
Publicado no Integr Biol (Camb) (2016)

Biodistribution and Pharmacokinetics Study of siRNA-loaded Anti-NTSR1-mAb-functionalized Novel Hybrid Nanoparticles in a Metastatic Orthotopic Murine Lung Cancer Model

Por Perepelyuk, Maryna, Thangavel, Chellappagounder, Liu, Yi, Den, Robert B, Lu, Bo, Snook, Adam E, Shoyele, Sunday A
Publicado no Mol Ther Nucleic Acids (2016)

Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury

Por Perepelyuk, Maryna, Terajima, Masahiko, Wang, Andrew Y., Georges, Penelope C., Janmey, Paul A., Yamauchi, Mitsuo, Wells, Rebecca G.
Publicado em 2013

Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics

Por Perepelyuk, Maryna, Chin, LiKang, Cao, Xuan, van Oosten, Anne, Shenoy, Vivek B., Janmey, Paul A., Wells, Rebecca G.
Publicado no PLoS One (2016)

siRNA-Encapsulated Hybrid Nanoparticles Target Mutant K-ras and Inhibit Metastatic Tumor Burden in a Mouse Model of Lung Cancer

Por Perepelyuk, Maryna, Shoyele, Olubunmi, Birbe, Ruth, Thangavel, Chellappagounder, Liu, Yi, Den, Robert B., Snook, Adam E., Lu, Bo, Shoyele, Sunday A.
Publicado no Mol Ther Nucleic Acids (2017)

Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation

Por Caliari, Steven R., Perepelyuk, Maryna, Cosgrove, Brian D., Tsai, Shannon J., Lee, Gi Yun, Mauck, Robert L., Wells, Rebecca G., Burdick, Jason A.
Publicado no Sci Rep (2016)