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Gradually softening hydrogels for modeling hepatic stellate cell behavior during fibrosis regression

The extracellular matrix (ECM) presents an evolving set of mechanical cues to resident cells. We developed methacrylated hyaluronic acid (MeHA) hydrogels containing both stable and hydrolytically degradable crosslinks to provide cells with a gradually softening (but not fully degradable) milieu, mim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Integr Biol (Camb)
Hauptverfasser: Caliari, Steven R., Perepelyuk, Maryna, Soulas, Elizabeth M., Lee, Gi Yun, Wells, Rebecca G., Burdick, Jason A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905794/
https://ncbi.nlm.nih.gov/pubmed/27162057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6ib00027d
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