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Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics

Tissues including liver stiffen and acquire more extracellular matrix with fibrosis. The relationship between matrix content and stiffness, however, is non-linear, and stiffness is only one component of tissue mechanics. The mechanical response of tissues such as liver to physiological stresses is n...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Perepelyuk, Maryna, Chin, LiKang, Cao, Xuan, van Oosten, Anne, Shenoy, Vivek B., Janmey, Paul A., Wells, Rebecca G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703410/
https://ncbi.nlm.nih.gov/pubmed/26735954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146588
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