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Hydrogels with Differential and Patterned Mechanics to Study Stiffness-Mediated Myofibroblastic Differentiation of Hepatic Stellate Cells

The differentiation of hepatic stellate cells (HSCs) into myofbroblasts is a key event in liver fibrosis. Due to the local stiffening of the extracellular matrix (ECM) during fibrosis, it is of great interest to develop mimics that can be used to investigate the cellular response to changes in mecha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guvendiren, Murat, Perepelyuk, Maryna, Wells, Rebecca G., Burdick, Jason A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045659/
https://ncbi.nlm.nih.gov/pubmed/24361340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2013.11.008
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