טוען...
Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery
Hesperadin, an established human Aurora B inhibitor, was tested against cultures of Trypanosoma brucei, Leishmania major, and Plasmodium falciparum, and was identified to be a potent proliferation inhibitor. A series of analogs was designed and tested to establish the initial structure-activity rela...
שמור ב:
| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4045489/ https://ncbi.nlm.nih.gov/pubmed/24910766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4MD00045E |
| תגים: |
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