Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson’s disease

Lignende værker

• Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network
  af: Chen, Sujuan, et al.
  Udgivet: (2013)
• N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain
  af: Chen, Sujuan, et al.
  Udgivet: (2014)
• Rotenone Induction of Hydrogen Peroxide Inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E Pathways, Leading to Neuronal Apoptosis
  af: Zhou, Qian, et al.
  Udgivet: (2015)
• Crosstalk between Ca(2+) signaling and mitochondrial H(2)O(2) is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis
  af: Liu, Chunxiao, et al.
  Udgivet: (2016)
• CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death
  af: Chen, Sujuan, et al.
  Udgivet: (2011)