Crosstalk between Ca(2+) signaling and mitochondrial H(2)O(2) is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis

Por Liu, Chunxiao, Ye, Yangjing, Zhou, Qian, Zhang, Ruijie, Zhang, Hai, Liu, Wen, Xu, Chong, Liu, Lei, Huang, Shile, Chen, Long
Publicado no Oncotarget (2016)

Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson’s disease...

Por Xu, Yijiao, Liu, Chunxiao, Chen, Sujuan, Ye, Yangjing, Guo, Min, Ren, Qian, Liu, Lei, Zhang, Hai, Xu, Chong, Zhou, Qian, Huang, Shile, Chen, Long
Publicado em 2014

N-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain

Por Chen, Sujuan, Ren, Qian, Zhang, Jinfei, Ye, Yangjing, Zhang, Zhen, Xu, Yijiao, Guo, Min, Ji, Haiyan, Xu, Chong, Gu, Chenjian, Gao, Wei, Huang, Shile, Chen, Long
Publicado em 2014