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Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network

Cadmium (Cd), a toxic environmental contaminant, induces neurodegenerative diseases. Celastrol, a plant-derived triterpene, has shown neuroprotective effects in various disease models. However, little is known regarding the effect of celastrol on Cd-induced neurotoxicity. Here, we show that celastro...

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Detalhes bibliográficos
Main Authors: Chen, Sujuan, Gu, Chenjian, Xu, Chong, Zhang, Jinfei, Xu, Yijiao, Ren, Qian, Guo, Min, Huang, Shile, Chen, Long
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183230/
https://ncbi.nlm.nih.gov/pubmed/24111524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12474
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