Differential regulation of the α-globin locus by Krüppel-like factor 3 in erythroid and non-erythroid cells

BACKGROUND: Krüppel-like Factor 3 (KLF3) is a broadly expressed zinc-finger transcriptional repressor with diverse biological roles. During erythropoiesis, KLF3 acts as a feedback repressor of a set of genes that are activated by Krüppel-like Factor 1 (KLF1). Noting that KLF1 binds α-globin gene reg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Funnell, Alister PW, Vernimmen, Douglas, Lim, Wooi F, Mak, Ka Sin, Wienert, Beeke, Martyn, Gabriella E, Artuz, Crisbel M, Burdach, Jon, Quinlan, Kate GR, Higgs, Douglas R, Whitelaw, Emma, Pearson, Richard CM, Crossley, Merlin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033687/
https://ncbi.nlm.nih.gov/pubmed/24885809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-15-8
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