Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor

Transcription factors (TFs) are often regarded as being composed of a DNA-binding domain (DBD) and a functional domain. The two domains are considered separable and autonomous, with the DBD directing the factor to its target genes and the functional domain imparting transcriptional regulation. We ex...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Burdach, Jon, Funnell, Alister P. W., Mak, Ka Sin, Artuz, Crisbel M., Wienert, Beeke, Lim, Wooi F., Tan, Lit Yeen, Pearson, Richard C. M., Crossley, Merlin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874204/
https://ncbi.nlm.nih.gov/pubmed/24106088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt895
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados