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Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factor
Transcription factors (TFs) are often regarded as being composed of a DNA-binding domain (DBD) and a functional domain. The two domains are considered separable and autonomous, with the DBD directing the factor to its target genes and the functional domain imparting transcriptional regulation. We ex...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874204/ https://ncbi.nlm.nih.gov/pubmed/24106088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt895 |
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