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Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain

Transcription factors are often regarded as having two separable components: a DNA-binding domain (DBD) and a functional domain (FD), with the DBD thought to determine target gene recognition. While this holds true for DNA binding in vitro, it appears that in vivo FDs can also influence genomic targ...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Lim, Wooi F., Burdach, Jon, Funnell, Alister P.W., Pearson, Richard C.M., Quinlan, Kate G.R., Crossley, Merlin
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838343/
https://ncbi.nlm.nih.gov/pubmed/26673701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1380
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