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Directing an artificial zinc finger protein to new targets by fusion to a non-DNA-binding domain
Transcription factors are often regarded as having two separable components: a DNA-binding domain (DBD) and a functional domain (FD), with the DBD thought to determine target gene recognition. While this holds true for DNA binding in vitro, it appears that in vivo FDs can also influence genomic targ...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838343/ https://ncbi.nlm.nih.gov/pubmed/26673701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1380 |
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