Influence of Phosphate and Phosphoesters on the Decomposition Pathway of 1,2-Bis(methylsulfonyl)-1-(2-chloroethyhydrazine (90CE), the Active Anticancer Moiety Generated by Laromustine, KS119, and KS119W

類似資料

• Influence of Glutathione and Glutathione S-transferases on DNA Interstrand Cross-Link Formation by 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine, the Active Anticancer Moiety Generated by Laromustine
  著者:: Penketh, Philip G., 等
  出版事項: (2014)
• Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumor cell resistance
  著者:: Baumann, Raymond P., 等
  出版事項: (2009)
• 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119): a Cytotoxic Prodrug with Two Stable Conformations Differing in Biological and Physical Properties
  著者:: Penketh, Philip G., 等
  出版事項: (2011)
• Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine
  著者:: Ishiguro, Kimiko, 等
  出版事項: (2006)
• Development of an O(6)-alkylguanine—DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-(3)H]O(6)-benzylguanine to the protein
  著者:: Ishiguro, Kimiko, 等
  出版事項: (2008)