1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119): a Cytotoxic Prodrug with Two Stable Conformations Differing in Biological and Physical Properties

অনুরূপ উপাদানগুলি

• Reductive activation of the prodrug 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine (KS119) selectively occurs in oxygen-deficient cells and overcomes O(6)-alkylguanine-DNA alkyltransferase mediated KS119 tumor cell resistance
  অনুযায়ী: Baumann, Raymond P., অন্যান্য
  প্রকাশিত: (2009)
• 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: An anticancer agent targeting hypoxic cells
  অনুযায়ী: Seow, Helen A., অন্যান্য
  প্রকাশিত: (2005)
• Influence of Phosphate and Phosphoesters on the Decomposition Pathway of 1,2-Bis(methylsulfonyl)-1-(2-chloroethyhydrazine (90CE), the Active Anticancer Moiety Generated by Laromustine, KS119, and KS119W
  অনুযায়ী: Penketh, Philip G., অন্যান্য
  প্রকাশিত: (2014)
• Influence of Glutathione and Glutathione S-transferases on DNA Interstrand Cross-Link Formation by 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine, the Active Anticancer Moiety Generated by Laromustine
  অনুযায়ী: Penketh, Philip G., অন্যান্য
  প্রকাশিত: (2014)
• Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine
  অনুযায়ী: Ishiguro, Kimiko, অন্যান্য
  প্রকাশিত: (2006)