A carregar...

Etoposide Quinone Is a Covalent Poison of Human Topoisomerase IIβ

[Image: see text] Etoposide is a topoisomerase II poison that is utilized to treat a broad spectrum of human cancers. Despite its wide clinical use, 2–3% of patients treated with etoposide eventually develop treatment-related acute myeloid leukemias (t-AMLs) characterized by rearrangements of the ML...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Smith, Nicholas A., Byl, Jo Ann W., Mercer, Susan L., Deweese, Joseph E., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033626/
https://ncbi.nlm.nih.gov/pubmed/24766193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500421q
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!