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Epimerization of Green Tea Catechins During Brewing Does Not Affect the Ability to Poison Human Type II Topoisomerases

(−)-Epigallocatechin gallate (EGCG) is the most abundant and biologically active polyphenol in green tea (Camellia sinensis) leaves and many of its cellular effects are consistent with its actions as a topoisomerase II poison. In contrast to genistein and several other related bioflavonoids that act...

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Detalhes bibliográficos
Main Authors: Timmel, M. Anne, Byl, Jo Ann W., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731400/
https://ncbi.nlm.nih.gov/pubmed/23514406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx4000667
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