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(−)-Epigallocatechin Gallate, A Major Constituent of Green Tea, Poisons Human Type II Topoisomerases

(−)-Epigallocatechin gallate (EGCG) is the most abundant and biologically active polyphenol in green tea, and many of the therapeutic benefits of the beverage have been attributed to this compound. High concentrations of EGCG are cytotoxic and trigger genotoxic events in mammalian cells. Although th...

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Detalhes bibliográficos
Main Authors: Bandele, Omari J., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893035/
https://ncbi.nlm.nih.gov/pubmed/18293940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700434v
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