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(−)-Epigallocatechin Gallate, A Major Constituent of Green Tea, Poisons Human Type II Topoisomerases

(−)-Epigallocatechin gallate (EGCG) is the most abundant and biologically active polyphenol in green tea, and many of the therapeutic benefits of the beverage have been attributed to this compound. High concentrations of EGCG are cytotoxic and trigger genotoxic events in mammalian cells. Although th...

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Autors principals: Bandele, Omari J., Osheroff, Neil
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893035/
https://ncbi.nlm.nih.gov/pubmed/18293940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700434v
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