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Cleavage of Plasmid DNA by Eukaryotic Topoisomerase II

Topoisomerase II is an essential enzyme that is required for a number of critical nuclear processes. All of the catalytic functions of topoisomerase II require the enzyme to generate a transient double-stranded break in the backbone of the double helix. To maintain genomic integrity during the cleav...

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Bibliographic Details
Main Authors: Bandele, Omari J., Osheroff, Neil
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893727/
https://ncbi.nlm.nih.gov/pubmed/19763940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60761-340-4_4
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