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The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

Topoisomerase II is an essential enzyme that is required for virtually every process that requires movement of DNA within the nucleus or the opening of the double helix. This enzyme helps to regulate DNA under- and overwinding and removes knots and tangles from the genetic material. In order to carr...

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Detalhes bibliográficos
Main Authors: Deweese, Joseph E., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647315/
https://ncbi.nlm.nih.gov/pubmed/19042970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn937
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