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The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

Topoisomerase II is an essential enzyme that is required for virtually every process that requires movement of DNA within the nucleus or the opening of the double helix. This enzyme helps to regulate DNA under- and overwinding and removes knots and tangles from the genetic material. In order to carr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deweese, Joseph E., Osheroff, Neil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647315/
https://ncbi.nlm.nih.gov/pubmed/19042970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn937
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