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The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

Topoisomerase II is an essential enzyme that is required for virtually every process that requires movement of DNA within the nucleus or the opening of the double helix. This enzyme helps to regulate DNA under- and overwinding and removes knots and tangles from the genetic material. In order to carr...

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Hlavní autoři: Deweese, Joseph E., Osheroff, Neil
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647315/
https://ncbi.nlm.nih.gov/pubmed/19042970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn937
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