A carregar...

Using 3’-Bridging Phosphorothiolates to Isolate the Forward DNA Cleavage Reaction of Human Topoisomerase IIα

The ability to cleave DNA is critical to the cellular and pharmacological functions of human type II topoisomerases. However, the low level of cleavage at equilibrium and the tight coupling of the cleavage and ligation reactions make it difficult to characterize the mechanism by which these enzymes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Deweese, Joseph E., Burgin, Alex B., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2733888/
https://ncbi.nlm.nih.gov/pubmed/18318502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702194x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!